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Aperio products are FDA cleared for specific clinical applications, and are intended for research and educational use for other applications. They are not approved by the FDA for primary diagnosis.
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Quintiles, the world’s largest CRO, partnered with Amicus to create a novel quantitative method to evaluate inclusions in renal capillaries. The study compared the accuracy of multiple readings made by pathologists using glass slides versus multiple readings made on annotated eSlides using the Aperio NETWORK under a GLP setting.
Accuracy rates using conventional glass slides:
Accuracy rates using the Aperio ePathology NETWORK:
Key Excerpt from the Study
“The virtual microscopy–based methodology increases accuracy and reproducibility; moreover, it provides a permanent record of retrievable data with full transparency in clinical trials.”
Reference
Barisoni L., Jennette JC, Colvin R, et al. Novel quantitative method to evaluate globotriaosylceramide inclusions in renal peritubular capillaries by virtual microscopy in patients with Fabry disease. Arch Pathol Lab Med. 2012; In Press.
It's simple. Just copy the following JavaScript and HTML into your web page at the point where you want the slide to be displayed:
<script type="text/javascript">
var vwidth, vheight, nx, ny, nwidth, nheight, zoom;
vwidth = 450; // set width of viewing window
vheight = 350; // set height of viewing window
nwidth = Math.round(vwidth / 3);
nheight = Math.round(vheight / 3);
nx = vwidth - nwidth - 5 - 1;
ny = 5;
zoom = -1;
awvhost="images2.aperio.com"; // set server with image
awvimage="Derm1.svs"; // set image name
awviewer="html/awv.swf";
awvvars = "awvImagePath=AWVIMAGE.apr&awvX=0.0&awvY=0.0&awvZoom=ZOOM&awvToolbar=1&awvNavWindow=1&awvSlider=1&awvGetURLBtn=0&awvAppMag=20&awvNavX=NX&awvNavY=NY&awvNavWidth=NWIDTH&awvNavHeight=NHEIGHT&awvHideAnnotations=";
function setDim(html) {
html = html.replace("AWVVARS", awvvars);
html = html.replace("AWVIMAGE", "Error! Hyperlink reference not valid);
html = html.replace("AWVIEWER", "Error! Hyperlink reference not valid);
html = html.replace("VWIDTH", vwidth);
html = html.replace("VHEIGHT", vheight);
html = html.replace("NX", nx);
html = html.replace("NY", ny);
html = html.replace("NWIDTH", nwidth);
html = html.replace("NHEIGHT", nheight);
html = html.replace("ZOOM", zoom);
document.write(html);
}
</script>
<table style="border: solid 2px black" cellpadding=0 cellspacing=0><tr><td>
<script type=text/javascript>setDim('<object id="theMovie" width=VWIDTH height=VHEIGHT classid="clsid:D27CDB6E-AE6D-11cf-96B8-444553540000" codebase="http://download.macromedia.com/pub/shockwave/cabs/flash/swflash.cab#version=6,0,40,0"><param name="src" value="AWVIEWER"><param name="FlashVars" value="AWVVARS">')</script>
<script type=text/javascript>setDim('<embed name="theMovie" width=VWIDTH height=VHEIGHT src="AWVIEWER" FlashVars="AWVVARS" type="application/x-shockwave-flash" pluginspage="http://www.macromedia.com/shockwave/download/index.cgi?P1_Prod_Version=ShockwaveFlash">')</script>
</embed>
</object>
</td></tr></table>
All you need to do is set the dimensions of the viewing window, and the server name and image file where the image is located (highlighted in blue above). Try it. Just another way Aperio puts the power of ePathology at your fingertips.
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