“The whole procedure usually takes 5-6 hours [5]. Here we present an automated RGC counting system, which scans the entire retina and counts its RGC nuclei in 14 minutes. Using this method, the RGC count of an entire drug screening study can be accomplished overnight.”
APERIO ePATHOLOGY SOLUTIONS FOR LIFE SCIENCE
The Biologic Revolution Demands More from Pathology
Pathology’s beginnings trace back to the Italian Renaissance, when physicians performed autopsies in an attempt to understand disease. The role of pathology has expanded dramatically since then ― influencing the entire scientific and medical continuum from research, bio-marker discovery, and safety studies, to intraoperative consults and personalized medicine.
We are now in the second decade of what is called the “Biologic Revolution” for Life Science. It’s essential that the maximum relevant biologic information be extracted from every specimen and shared among collaborators efficiently and expediently. Conventional glass slides do not support these capabilities or whole slide image analysis. Sharing glass slides among scientific peers or study partners have added complications―inaccurate scoring, inconsistent conclusions, and the difficulty of gaining concordance among pathologists. Additionally, there is the time, expense, and resources lost with glass shipping and tracking as well as travel for consults. Manual analytic processes are time-consuming and tedious and only scratch the surface of what the researcher can learn about the specimen.
Organizations stuck in these manual and outdated analog processes cannot access their data fast enough―and when they do, the data itself may be insufficient to support a decision. Today’s Life Science teams are challenged to keep pace with technological advancements and the demand to produce more with fewer resources. The labor and time intensive processes of current pathology practice have proven themselves to be too unyielding. Pathologists are looking to new technologies to help them further unleash their skills and collaborate more easily.
The evolution of Pathology
The “e” Life Science era has arrived
Aperio recognized that analog processes were a major impediment to progress in pathology for both healthcare and life science organizations. This insight was the catalyst for us to be the first to develop the technology to transform microscopic glass slides into whole slide digital images, eSlides. Aperio ePathology Solutions equip organizations, including biopharma, CROs, and research institutions around the world, to transcend these barriers and reduce study times and costs.
The evolution of Pathology
Aperio ePathology Solutions:
NETWORK and PRECISION Image Analysis
For over a decade, Aperio has advanced the technology that enables glass slides to be converted into whole slide digital images, eSlides, which can be easily managed and securely shared with others. Our interoperable, scalable, and secure, web-based eSlide Manager software streamlines accessing, archiving, sorting, and searching of eSlides and study records. The NETWORK supports remote, simultaneous, real-time viewing and rapid distribution of eSlides and study records for peer review and streamlined collaboration under GLP. Our PRECISION Image Analysis Solution empowers pathologists with easy to use analytic tools that improve consistency, accuracy, and reproducibility of study data while reducing time to results.
Rely on Aperio ePathology expertise
From the beginning, our sole focus has been pathology. We were the first to develop the technology to transform microscopic glass slides into whole slide digital images, eSlides. We leveraged our understanding of the science and processes of pathology to create our end-to-end Aperio ePathology Solutions: NETWORK and PRECISION Image Analysis.
Aperio ePathology Solutions have been cited in over 400 peer-reviewed publications. In fact, a recent scientific study documented that the use of our annotated eSlides raised pathologists’ intra-and inter-reader accuracy to >90% relative accuracy.
With more Life Science systems installed globally than all other providers combined, we have the experience and expertise to ensure a successful implementation in your organization.
Whether performing basic research, biomarker discovery, drug safety, or toxicologic pathology studies, Aperio ePathology Solutions equip teams to accelerate innovation and increase productivity. Find out what Aperio’s ePathology Solutions can do for your organization.
NETWORK
We enable glass slides to become whole-slide digital eSlides, and then, via our NETWORK, we support global real-time viewing of eSlides and study records for rapid distribution, peer review and streamlined collaboration under GLP. And it's all seamlessly integrated with our scalable and secure web-based eSlide Manager Software Platform.
PRECISION Image Analysis
Our PRECISION Image Analysis Solution enables and supports easy to use analytic tools that improve consistency, accuracy and reproducibility of study data while reducing time to results. Once analyzed, the eSlides and analysis data are seamlessly integrated with our scalable and secure web-based eSlide Manager Software.
eSlide Manager
Our powerful eSlide Manager Software allows you to easily run studies from start to finish via a central hub that can scale across organizations. Effortlessly and efficiently CAPTURE, VIEW, MANAGE, ANALYZE and Archive whole eSlides.
Capture
Aperio is driving a global market shift from core-scanning technology to global, end-to-end solutions.
Team Benefits
Histologist
Easily create and distribute eSlides.Read more
Pathologist
Reduce study times; decide sooner.Read more
CSO
Accelerate innovation; reduce study costs.Read more
IT
Optimize data management.Read more
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What People Are Saying
Yaacobi Y, Ca S, Li B, et al. A Novel, Automated, High Throughput Retinal Ganglion Cell Counting System
Alcon Research, Fort Worth, TX
“The success of (GENIE- Aperio’s Solutions) has significantly reduced the time taken to deliver IHC image analysis results from PD studies by avoiding manual mark up.”
AstraZeneca
The Aperio NETWORK, enables streamlined collaboration and seamless integration with our scalable and secure, web-based eSlide Manager software. Our PRECISION Image Analysis tools empower pathologists with easy to use, quantitative capabilities that improve reproducibility and reduce analysis time.
With the NEW Aperio Image Analysis Toolbox, the ability to analyze stain area and intensity, colocalization of multiple dyes, cell-based biomarkers, and objects such as plaques and microvessels, allows researchers to extract more data than ever before from their fluorescent whole slide images.